GPR77 Protein (Fc Tag)

Produktnummer ABIN7092820

Produktdetails

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GPR77 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human GPR77(1-38) with C-terminal human Fc tag

Spezifität: GPR77 (Met1-Pro38) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Andere Bezeichnung: GPR77 (GPR77 Produkte)

Synonyme: GPR77 Protein, C5L2 Protein, GPF77 Protein, E030029A11Rik Protein, Gpr77 Protein, complement component 5a receptor 2 Protein, C5AR2 Protein, C5ar2 Protein

Hintergrund: Synonymes: C5L2
Description: This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Molekulargewicht: predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of GPR77(1-38)-hFc is 35-55 kDa due to glycosylation.

UniProt: Q9P296