IgG1 Protein (Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant) (His tag)
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- Target Alle IgG1 Proteine anzeigen
- IgG1
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IgG1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag
- Sequenz
- Glu 99 - Lys 330
- Produktmerkmale
- Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, M135Y, S137T, T139E, H316K, N317F).
- Reinheit
- 95,00 %
- Endotoxin-Niveau
- 1.0 EU per μg
- Top Product
- Discover our top product IgG1 Protein
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- Kommentare
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.1 kDa. The protein migrates as 30-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C
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- Target
- IgG1
- Abstract
- IgG1 Produkte
- Synonyme
- IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein
- Substanzklasse
- Antibody
- Hintergrund
- Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
- Molekulargewicht
- 28.1 kDa
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