IgG1 Protein (Cys103Ser-Mutant, Leu117Phe-Mutant, Leu118Glu-Mutant, Pro214Ser-Mutant) (His tag)

Produktnummer ABIN7271665

Produktdetails

Target: IgG1

Protein-Typ: Recombinant

Proteineigenschaft: Cys103Ser-Mutant, Leu117Phe-Mutant, Leu118Glu-Mutant, Pro214Ser-Mutant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IgG1 Protein ist gelabelt mit His tag.

Verwendungszweck: Human IgG1 Fc (C103S, L117F, L118E, P214S) Protein, His Tag

Sequenz: Glu 99 - Lys 330

Produktmerkmale: Human IgG1 Fc (C103S, L117F, L118E, P214S), His Tag (IG1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, L117F, L118E, P214S).

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28 kDa. The protein migrates as 30-33 kDa under reducing (R) condition due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: IgG1

Abstract: IgG1 Produkte

Synonyme: IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein

Substanzklasse: Antibody

Hintergrund: Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Molekulargewicht: 28 kDa