HHLA2 Protein (Biotin,Fc-Avi Tag)
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- Target Alle HHLA2 Proteine anzeigen
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses HHLA2 Protein ist gelabelt mit Biotin,Fc-Avi Tag.
- Verwendungszweck
- Biotinylated Human B7-H7 / HHLA2 Protein, Fc,Avitag™ (MALS verified)
- Sequenz
- Ile 23 - Asn 344
- Produktmerkmale
- Biotinylated Human B7-H7 / HHLA2, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asn 344 (Accession # Q9UM44-1).
- Reinheit
- 95,00 %
- Endotoxin-Niveau
- 1.0 EU per μg
- Güteklasse
- MALS verified
- Top Product
- Discover our top product HHLA2 Protein
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- Kommentare
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This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 65.1 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- 51 mM Tris,100 mM Glycine,25 mM Arginine,150 mM NaCl
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C
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- Target
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Andere Bezeichnung
- B7-H7 (HHLA2 Produkte)
- Synonyme
- B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
- Hintergrund
- Synonyms:B7-H7,HHLA2,B7 Homolog 7,Description:B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
- Molekulargewicht
- 65.1 kDa
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