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HHLA2 Protein (Biotin,Fc-Avi Tag)

MALS verified HHLA2 Spezies: Human Wirt: HEK-293 Cells Recombinant 95,00 %
Produktnummer ABIN7316780
  • Target Alle HHLA2 Proteine anzeigen
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 2
    Human
    Quelle
    • 7
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses HHLA2 Protein ist gelabelt mit Biotin,Fc-Avi Tag.
    Verwendungszweck
    Biotinylated Human B7-H7 / HHLA2 Protein, Fc,Avitag™ (MALS verified)
    Sequenz
    Ile 23 - Asn 344
    Produktmerkmale
    Biotinylated Human B7-H7 / HHLA2, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asn 344 (Accession # Q9UM44-1).
    Reinheit
    95,00 %
    Endotoxin-Niveau
    1.0 EU per μg
    Güteklasse
    MALS verified
    Top Product
    Discover our top product HHLA2 Protein
  • Kommentare

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 65.1 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    51 mM Tris,100 mM Glycine,25 mM Arginine,150 mM NaCl
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Andere Bezeichnung
    B7-H7 (HHLA2 Produkte)
    Synonyme
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Hintergrund
    Synonyms:B7-H7,HHLA2,B7 Homolog 7,Description:B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
    Molekulargewicht
    65.1 kDa
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