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HHLA2 Protein (AA 23-344) (Fc Tag)

HHLA2 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
Produktnummer ABIN6809928
  • Target Alle HHLA2 Proteine anzeigen
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 23-344
    Spezies
    • 7
    • 2
    Human
    Quelle
    • 7
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses HHLA2 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 23-344
    Reinheit
    >90 % as determined by reduced SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product HHLA2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
  • Target
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Andere Bezeichnung
    B7-H7 (HHLA2 Produkte)
    Synonyme
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Hintergrund
    B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
    Molekulargewicht
    63.4 kDa
    NCBI Accession
    NP_009003
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