VLDLR Protein (AA 28-797) (His tag)

Produktnummer ABIN7275822

Produktdetails

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 28-797

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses VLDLR Protein ist gelabelt mit His tag.

Verwendungszweck: Human VLDLR Protein

Sequenz: Gly28-Ser797

Produktmerkmale: Recombinant Human VLDLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly28-Ser797.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 9.78 μM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Andere Bezeichnung: VLDLR (VLDLR Produkte)

Synonyme: CARMQ1 Protein, CHRMQ1 Protein, VLDLRCH Protein, AA408956 Protein, AI451093 Protein, AW047288 Protein, vldlr Protein, very low density lipoprotein receptor Protein, very low density lipoprotein receptor S homeolog Protein, VLDLR Protein, Vldlr Protein, vldlr.S Protein

Hintergrund: VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk and preimplantation genetic testing are possible when the pathogenic variants in a family are known.

Molekulargewicht: 85.9 kDa. Due to glycosylation, the protein migrates to 115-125 kDa based on Tris-Bis PAGE result.

Pathways: Cellular Response to Molecule of Bacterial Origin