Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-769) (Active) protein (His tag) Protein
- Target Alle VLDLR Proteine anzeigen
- Biologische Aktivität
- AA 28-769
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses VLDLR Protein ist gelabelt mit His tag.
- AA 28-769
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 83 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
- >90 % as determined by SDS-PAGE.
- 0.22 μm filtered
- Less than 1.0 EU per μg by the LAL method.
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-873) protein (rho-1D4 tag) Protein
Crystallography grade VLDLR Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WBVery Low Density Lipoprotein Receptor (VLDLR) (AA 28-797) protein (His tag) Protein
Crystallography grade VLDLR Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
- Nur für Forschungszwecke einsetzbar
- PBS, pH 7.4
- Please avoid repeated freeze-thaw cycles.
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
- Andere Bezeichnung
- VLDL R (VLDLR Produkte)
- CARMQ1, CHRMQ1, VLDLRCH, AA408956, AI451093, AW047288, vldlr, very low density lipoprotein receptor, very low density lipoprotein receptor S homeolog, VLDLR, Vldlr, vldlr.S
- The very-low-density-lipoprotein receptor (VLDL-R) is a lipoprotein receptor that shows considerable similarity to the lowdensity-lipoprotein receptor. VLDL R is a 130 kDa type I transmembrane protein in the LDL receptor family that plays a significant role in lipid metabolism and in nervous system development and function .This receptor has been suggested to be important for the metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, such as very-low-densitylipoprotein (VLDL), beta-migrating VLDL and intermediate-density lipoprotein. It is also one of the receptors of reelin, an extracellular matrix protein which regulates the processes of neuronal migration and synaptic plasticity. In humans, the VLDL-R is encoded by the VLDLR gene. A rare neurological disorder first described in the 1970s under the name "disequilibrium syndrome" is now considered to be caused by the disruption of VLDLR gene. The disorder was renamed VLDLR-associated cerebellar hypoplasia (VLDLRCH) after a 2005 study. It is associated with parental consanguinity and found in secluded communities such as the Hutterites. VLDLRCH is one of the two known genetic disorders caused by a disruption of reelin signaling pathway, along with Norman-Roberts syndrome.
- 84.0 kDa
- Cellular Response to Molecule of Bacterial Origin