TACSTD2
(Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
Protein-Typ
Recombinant
Proteineigenschaft
AA 27-274
Spezies
Human
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses TACSTD2 Protein ist gelabelt mit His tag.
Verwendungszweck
Human TROP-2/TACSTD2 Protein
Sequenz
His27-Thr274
Produktmerkmale
Recombinant Human TROP-2/TACSTD2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His27-Thr274.
Reinheit
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sterilität
0.22 μm filtered
Endotoxin-Niveau
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human TROP-2, His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Anti-Trop2 Ab., hFc Tag with the EC50 of 6.7ng/ml determined by ELISA. See testing image for detail.
TACSTD2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
TACSTD2
Spezies: Human
Wirt: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
Active
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Lagerung
-20 °C,-80 °C
Informationen zur Lagerung
-20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Haltbarkeit
12 months
Target
TACSTD2
(Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Molekulargewicht
28.9 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result.