TACSTD2 Protein (Fc Tag)

Produktnummer ABIN7319895

Produktdetails

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses TACSTD2 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-Fc)

Sequenz: His27-Thr274

Produktmerkmale: Recombinant Human Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding His27-Thr274 is expressed with a Fc tag at the C-terminus.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human TROP-2-Fc(Cat#C07Y) at 2μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb*.*: Biotinylated by NHS-biotin prior to testing. The ED50 of Anti-Human TROP-2 mAb* is 20.54 ng/ml.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Andere Bezeichnung: Tumor-associated Calcium Signal Transducer 2/TROP-2 (TACSTD2 Produkte)

Synonyme: EGP-1 Protein, EGP1 Protein, GA733-1 Protein, GA7331 Protein, GP50 Protein, M1S1 Protein, TROP2 Protein, C80403 Protein, Ly97 Protein, Prp1 Protein, tumor associated calcium signal transducer 2 Protein, tumor-associated calcium signal transducer 2 Protein, TACSTD2 Protein, Tacstd2 Protein

Hintergrund:

Background: Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87 % amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

Synonym: Tumor-associated calcium signal transducer 2, Membrane component chromosome 1 surface marker 1, Cell surface glycoprotein Trop-2, TACSTD2, TROP2

Molekulargewicht: 54.8 kDa

UniProt: P09758