Syndecan 1 Protein (SDC1) (AA 23-254) (Fc Tag)

Produktnummer ABIN7275678

Produktdetails

Target: Syndecan 1 (SDC1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-254

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Syndecan 1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human Syndecan-1 Protein

Sequenz: Gln23-Gly254

Produktmerkmale: Recombinant Human Syndecan-1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln23-Gly254.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human Syndecan-1, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-Syndecan-1 Antibody, hFc Tag with the EC50 of 19.2ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: Syndecan-1 (SDC1 Produkte)

Synonyme: CG10497 Protein, CT27296 Protein, Dmel\\CG10497 Protein, Dsyn Protein, Syd Protein, Syn Protein, dSdc Protein, l(2)10608 Protein, sdc Protein, syd Protein, syn Protein, Syn1 Protein, cd138 Protein, synd1 Protein, xSyn1 Protein, syndecan1 Protein, Syndecan-1 Protein, XSyndecan-1 Protein, SDC1 Protein, CD138 Protein, SDC Protein, SYND1 Protein, syndecan Protein, AA408134 Protein, AA409076 Protein, Sstn Protein, Synd Protein, Synd1 Protein, syn-1 Protein, HSPG Protein, SYNDECA Protein, Syndecan Protein, Syndecan Protein, syndecan 1 Protein, Sdc Protein, sdc1 Protein, SDC1 Protein, Sdc1 Protein

Hintergrund: Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver.

Molekulargewicht: 50.6 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result.

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism