SFRP2 Protein (AA 25-295) (His tag)

Produktnummer ABIN7275649

Produktdetails

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 25-295

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SFRP2 Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus SFRP2 Protein

Sequenz: Leu25-Cys295

Produktmerkmale: Recombinant Cynomolgus SFRP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu25-Cys295.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Andere Bezeichnung: SFRP2 (SFRP2 Produkte)

Synonyme: frp-2 Protein, sarp1 Protein, sdf-5 Protein, sfrp-2 Protein, SFRP2 Protein, sfrp2 Protein, FRP-2 Protein, SARP1 Protein, SDF-5 Protein, AI851596 Protein, Sdf5 Protein, hm:zeh0225 Protein, zeh0225 Protein, zgc:153618 Protein, SFRP-2 Protein, secreted frizzled-related protein 2 Protein, secreted frizzled related protein 2 Protein, secreted frizzled-related protein 2 S homeolog Protein, secreted frizzled-related protein Protein, sfrp2 Protein, sfrp2 Protein, SFRP2 Protein, sfrp2.S Protein, LOAG_01461 Protein, Sfrp2 Protein

Hintergrund: As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in the Wnt signaling pathway, and the prognosis of CRC were not consistent. SFRP1, SFRP2, and WIF1 were frequently hypermethylated in CRC tumor tissues. It was apparent that the promoter hypermethylation of SFRP2 and co-hypermethylation of SFRP1 and SFRP2 might be considered as independent prognostic predictors for survival advantage of postoperative CRC patients.

Molekulargewicht: 32.16 kDa. Due to glycosylation, the protein migrates to 33-38 kDa based on Tris-Bis PAGE result.

UniProt: G8F2Z7

Pathways: WNT Signalweg, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation