SFRP1 Protein (AA 32-314) (His tag)

Produktnummer ABIN7275578

Produktdetails

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 32-314

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SFRP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Human SFRP1/SARP2 Protein

Sequenz: Ser32-Lys314

Produktmerkmale: Recombinant Human SFRP1/SARP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser32-Lys314.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1 (SFRP1 Produkte)

Synonyme: FRP Protein, FRP-1 Protein, FRP1 Protein, FrzA Protein, SARP2 Protein, 2210415K03Rik Protein, AW011917 Protein, AW107218 Protein, AW742929 Protein, sFRP-1 Protein, CSFRP1 Protein, SFRP1 Protein, XfrzA Protein, frp Protein, frp-1 Protein, frp1 Protein, frzA Protein, sarp2 Protein, sfrp1 Protein, LOC100231868 Protein, Srfp1a Protein, wu:fd19b09 Protein, secreted frizzled related protein 1 Protein, secreted frizzled-related protein 1 Protein, Secreted frizzled-related protein 1 Protein, secreted frizzled-related protein 1a Protein, secreted frizzled-related protein 1b Protein, SFRP1 Protein, Sfrp1 Protein, sfrp1 Protein, sfrp1a Protein, sfrp1b Protein

Hintergrund: Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to the loss of expression in various human cancers, which is mainly attributed by epigenetic inactivation via DNA methylation or transcriptional silencing by microRNAs.

Molekulargewicht: 33.63 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result.

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation