APCS Protein (AA 20-223) (Fc Tag)

Produktnummer ABIN7275545

Produktdetails

Target: APCS (Amyloid P Component, Serum (APCS))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-223

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses APCS Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human Pentraxin 2/SAP Protein

Sequenz: His20-Val223

Produktmerkmale: Recombinant Human Pentraxin 2/SAP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His20-Val223.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human Pentraxin 2, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 58.2ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: APCS (Amyloid P Component, Serum (APCS))

Andere Bezeichnung: Pentraxin 2 (APCS Produkte)

Synonyme: PTX2 Protein, SAP Protein, Sap Protein, APCS Protein, FP Protein, SAP(FP) Protein, apcs Protein, ptx2 Protein, sap Protein, amyloid P component, serum Protein, serum amyloid P-component Protein, amyloid P component, serum protein L homeolog Protein, APCS Protein, Apcs Protein, apcs.L Protein

Hintergrund: Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20 % , and improving histological signs of disease. diseases.

Molekulargewicht: 50 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.

UniProt: P02743