NOTCH2 Protein (His-Avi Tag,Biotin)
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- Target Alle NOTCH2 Proteine anzeigen
- NOTCH2 (Notch 2 (NOTCH2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses NOTCH2 Protein ist gelabelt mit His-Avi Tag,Biotin.
- Sequenz
- Leu26-Gln530
- Reinheit
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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Notch 2 (NOTCH2) (AA 26-530) (Active) protein (Fc Tag)
NOTCH2 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Notch 2 (NOTCH2) (AA 27-136) protein (GST tag)NOTCH2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Notch 2 (NOTCH2) protein (His tag)NOTCH2 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Notch 2 (NOTCH2) (AA 1699-2471) protein (His tag)Crystallography grade NOTCH2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1699-2470) protein (His tag)Crystallography grade NOTCH2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1666-2471) protein (rho-1D4 tag)Crystallography grade NOTCH2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1697-2471) protein (rho-1D4 tag)Crystallography grade NOTCH2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1666-2470) protein (rho-1D4 tag)Crystallography grade NOTCH2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1697-2470) protein (rho-1D4 tag)Crystallography grade NOTCH2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NOTCH2 (Notch 2 (NOTCH2))
- Andere Bezeichnung
- Notch 2 (NOTCH2 Produkte)
- Synonyme
- AGS2 Protein, HJCYS Protein, hN2 Protein, AI853703 Protein, N2 Protein, notch6 Protein, sb:cb884 Protein, neurogenic locus notch homolog protein 2 Protein, notch 2 Protein, notch 3 Protein, LOC581186 Protein, NOTCH2 Protein, notch3 Protein, Notch2 Protein, notch2 Protein
- Hintergrund
- AGS2, Notch-2, NOTCH2, N2ECD, HJCYS, N2,Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch-2 is lethal, showing that not all functions overlap.Notch-2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
- Molekulargewicht
- 57 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- UniProt
- Q04721
- Pathways
- Notch Signalweg, Stem Cell Maintenance
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