KIR2DL3 Protein (AA 22-245) (His-Avi Tag)
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- Target Alle KIR2DL3 Proteine anzeigen
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 22-245
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses KIR2DL3 Protein ist gelabelt mit His-Avi Tag.
- Verwendungszweck
- Human KIR2DL3 Protein
- Sequenz
- His22-His245
- Produktmerkmale
- Recombinant Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) protein (His-Avi Tag,Biotin)
KIR2DL3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 1-341) protein (GST tag)KIR2DL3 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) protein (His tag)Crystallography grade KIR2DL3 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-341) protein (rho-1D4 tag)Crystallography grade KIR2DL3 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- Andere Bezeichnung
- KIR2DL3 (KIR2DL3 Produkte)
- Synonyme
- CD158B2 Protein, CD158b Protein, GL183 Protein, KIR-023GB Protein, KIR-K7b Protein, KIR-K7c Protein, KIRCL23 Protein, NKAT Protein, NKAT2 Protein, NKAT2A Protein, NKAT2B Protein, p58 Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 Protein, KIR2DL3 Protein
- Hintergrund
- KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
- Molekulargewicht
- 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.
- UniProt
- P43628
- Pathways
- Cancer Immune Checkpoints
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