IL5RA Protein (AA 21-335) (His-Avi Tag)

Produktnummer ABIN7275034

Produktdetails

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-335

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL5RA Protein ist gelabelt mit His-Avi Tag.

Verwendungszweck: Human IL-5 R alpha/CD125 Protein

Sequenz: Asp21-Glu335

Produktmerkmale: Recombinant Human IL-5 R alpha/CD125 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp21-Glu335.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 4.9nM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Andere Bezeichnung: IL-5 R alpha (IL5RA Produkte)

Synonyme: MGC86517 Protein, IL5RA Protein, il5r Protein, cdw125 Protein, hsil5r3 Protein, gpIL-5ra Protein, CD125 Protein, CDw125 Protein, HSIL5R3 Protein, IL5R Protein, Il5r Protein, interleukin 5 receptor subunit alpha L homeolog Protein, interleukin 5 receptor subunit alpha Protein, interleukin 5 receptor, alpha Protein, il5ra.L Protein, IL5RA Protein, il5ra Protein, Il5ra Protein

Hintergrund: Interleukin-5 Receptor alpha (IL-5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.

Molekulargewicht: 38.7 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Tris-Bis PAGE result.

Pathways: JAK-STAT Signalweg