IL-21 Protein (AA 32-162) (His-Avi Tag,Biotin)

Produktnummer ABIN7274917

Produktdetails

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Protein-Typ: Recombinant

Proteineigenschaft: AA 32-162

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses IL-21 Protein ist gelabelt mit His-Avi Tag,Biotin.

Verwendungszweck: Biotinylated Human IL-21 Protein

Sequenz: Gln32-Ser162

Produktmerkmale: Recombinant Biotinylated Human IL-21 Protein is expressed from E.coli with His tag and Avi tag at the N-Terminus.It contains Gln32-Ser162.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human IL-21R, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human IL-21, His Tag with the EC50 of 3.5ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 20 mM NaAc, 500 mM NaCl ( pH 5.5).

Buffer: Lyophilized from 0.22 μm filtered solution in 20 mM NaAc, 500 mM NaCl ( pH 5.5). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Andere Bezeichnung: IL-21 (IL21 Produkte)

Synonyme: IL-21 Protein, Za11 Protein, interleukin 21 Protein, IL21 Protein, Il21 Protein

Hintergrund: Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases.

Molekulargewicht: 18.30 kDa same as Tris-Bis PAGE result.

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response