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Osteoactivin Protein (GPNMB) (AA 23-502) (His tag)

GPNMB Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274754
  • Target Alle Osteoactivin (GPNMB) Proteine anzeigen
    Osteoactivin (GPNMB)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 23-502
    Spezies
    • 15
    • 2
    Maus
    Quelle
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Osteoactivin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Mouse Osteoactivin/GPNMB Protein
    Sequenz
    Lys23-Asn502
    Produktmerkmale
    Recombinant Mouse Osteoactivin/GPNMB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys23-Asn502.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Osteoactivin (GPNMB)
    Andere Bezeichnung
    Osteoactivin (GPNMB Produkte)
    Synonyme
    HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein
    Hintergrund
    GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative diseases and cancer.
    Molekulargewicht
    54.7 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    NP_444340
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