Osteoactivin Protein (GPNMB) (AA 22-486) (His tag)

Produktnummer ABIN7319322

Produktdetails

Target: Osteoactivin (GPNMB)

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-486

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Osteoactivin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GPNMB Protein (aa 22-486, His Tag)

Sequenz: Ala22-Pro486

Produktmerkmale: Recombinant Human Glycoprotein Non-Metastatic Melanoma Protein B is produced by our Mammalian expression system and the target gene encoding Ala22-Pro486 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Osteoactivin (GPNMB)

Andere Bezeichnung: GPNMB (GPNMB Produkte)

Synonyme: HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein

Hintergrund:

Background: Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.

Synonym: Transmembrane Glycoprotein NMB, Transmembrane Glycoprotein HGFIN, GPNMB, HGFIN,NMB,Osteoactivin

Molekulargewicht: 53.1 kDa