EPH Receptor B3 Protein (EPHB3) (AA 30-554) (His tag)

Produktnummer ABIN7274566

Produktdetails

Target: EPH Receptor B3 (EPHB3)

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-554

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EPH Receptor B3 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse EphB3 Protein

Sequenz: Leu30-Leu554

Produktmerkmale: Recombinant Mouse EphB3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu30-Leu554.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: EPH Receptor B3 (EPHB3)

Andere Bezeichnung: EphB3 (EPHB3 Produkte)

Synonyme: tck Protein, MGC83457 Protein, EPHB3 Protein, ETK2 Protein, HEK2 Protein, TYRO6 Protein, AW456895 Protein, Cek10 Protein, Etk2 Protein, MDK5 Protein, Sek4 Protein, Tyro6 Protein, CEK10 Protein, EK10 Protein, ek3 Protein, ephb3 Protein, fc62d03 Protein, rtk3 Protein, wu:fc62d03 Protein, zek3 Protein, EPH receptor B3 Protein, EPH receptor B3 L homeolog Protein, Eph receptor B3 Protein, eph receptor B3a Protein, Eph receptor tyrosine kinase Protein, EPHB3 Protein, ephb3.L Protein, ephb3 Protein, Ephb3 Protein, ephb3a Protein

Hintergrund: Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.

Molekulargewicht: 58.4 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

UniProt: P54754

Pathways: RTK Signalweg