EPH Receptor A10 Protein (EPHA10) (AA 34-565) (His tag)

Produktnummer ABIN7274548

Produktdetails

Target: EPH Receptor A10 (EPHA10)

Protein-Typ: Recombinant

Proteineigenschaft: AA 34-565

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EPH Receptor A10 Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus EPHA10 Protein

Sequenz: Glu34-Ala565

Produktmerkmale: Recombinant Cynomolgus EPHA10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu34-Ala565.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: EPH Receptor A10 (EPHA10)

Andere Bezeichnung: EPHA10 (EPHA10 Produkte)

Synonyme: A330090H18 Protein, RGD1562679 Protein, EPH receptor A10 Protein, Eph receptor A10 Protein, EPHA10 Protein, Epha10 Protein

Hintergrund: EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in normal tissues in some cancer types, including pancreatic cancer.EphA10 silencing reduced the proliferation, migration, and adhesion of MIA PaCa-2 and AsPC-1 pancreatic cancer cells. EphA10 plays a pivotal role in the tumorigenesis of pancreatic epithelial cells and is a novel therapeutic target for pancreatic cancer.

Molekulargewicht: 58.56 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_045230088

Pathways: RTK Signalweg