Desmoglein 3 Protein (DSG3) (AA 50-615) (His tag)
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- Target Alle Desmoglein 3 (DSG3) Proteine anzeigen
- Desmoglein 3 (DSG3)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 50-615
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Desmoglein 3 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Human DSG3 Protein
- Sequenz
- Glu50-Arg615
- Produktmerkmale
- Recombinant Human DSG3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu50-Arg615.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human DSG3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-DSG3 Antibody, hFc Tag with the EC50 8.5ng/ml determined by ELISA. See testing image for detail.
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Desmoglein 3 (DSG3) (AA 50-617) protein (His tag)
DSG3 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Desmoglein 3 (DSG3) (AA 50-615) protein (His tag)Crystallography grade DSG3 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Desmoglein 3 (DSG3) (AA 641-999) protein (His tag)Crystallography grade DSG3 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Desmoglein 3 (DSG3) (AA 639-993) protein (His tag)Crystallography grade DSG3 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Desmoglein 3 (DSG3) (AA 50-617) protein (His tag)Crystallography grade DSG3 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Desmoglein 3 (DSG3) (AA 50-999) protein (rho-1D4 tag)Crystallography grade DSG3 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Desmoglein 3 (DSG3) (AA 50-993) protein (rho-1D4 tag)Crystallography grade DSG3 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Desmoglein 3 (DSG3) (AA 50-615) protein (His-SUMO Tag)DSG3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Desmoglein 3 (DSG3)
- Andere Bezeichnung
- DSG3 (DSG3 Produkte)
- Synonyme
- DSG3 Protein, CDHF6 Protein, PVA Protein, bal Protein, balding Protein, desmoglein 3 Protein, DSG3 Protein, Dsg3 Protein
- Hintergrund
- To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.
- Molekulargewicht
- 64 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result.
- UniProt
- P32926
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