DDR2 Protein (AA 22-399) (His tag)

Produktnummer ABIN7274461

Produktdetails

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-399

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DDR2 Protein ist gelabelt mit His tag.

Verwendungszweck: Human DDR2 Protein

Sequenz: Lys22-Arg399

Produktmerkmale: Recombinant Human DDR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys22-Arg399.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Andere Bezeichnung: DDR2 (DDR2 Produkte)

Synonyme: MIG20a Protein, NTRKR3 Protein, TKT Protein, TYRO10 Protein, AW495251 Protein, Ntrkr3 Protein, tyro10 Protein, DDR2 Protein, Tyro10 Protein, ddr2 Protein, si:ch211-193c2.1 Protein, discoidin domain receptor tyrosine kinase 2 Protein, discoidin domain receptor family, member 2 Protein, discoidin domain receptor family, member 2, like Protein, DDR2 Protein, Ddr2 Protein, ddr2l Protein

Hintergrund: Discoidin domain receptor (DDR) 2 is a collagen receptor that is implicated in several cancer types including breast and prostate cancers. DDR2 might be closely associated with ovarian cancer progression and metastasis. Its high expression may serve as a potential prognostic biomarker in human ovarian cancer.

Molekulargewicht: 43.80 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

UniProt: Q16832

Pathways: RTK Signalweg