CLEC12A Protein (AA 65-265) (Fc Tag)

Produktnummer ABIN7274353

Produktdetails

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 65-265

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CLEC12A Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human CLEC12A/MICL/CLL-1 Protein

Sequenz: His65-Ala265

Produktmerkmale: Recombinant Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains His65-Ala265.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CLEC12A, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC12A Antibody, hFc Tag with the EC50 of 34.8ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Andere Bezeichnung: CLEC12A (CLEC12A Produkte)

Synonyme: MGC179455 Protein, CLL-1 Protein, CLL1 Protein, DCAL-2 Protein, MICL Protein, D230024O04 Protein, KLRL1 Protein, Micl Protein, C-type lectin domain family 12 member A Protein, C-type lectin domain family 12, member a Protein, C-type lectin domain family 12, member A Protein, CLEC12A Protein, Clec12a Protein

Hintergrund: CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.

Molekulargewicht: 50.9 kDa. Due to glycosylation, the protein migrates to 68-73 kDa based on Tris-Bis PAGE result.