Adipsin Protein (AA 26-253) (Fc Tag)

Produktnummer ABIN7274335

Produktdetails

Target: Adipsin (CFD) (Complement Factor D (CFD))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-253

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Adipsin Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human Complement Factor D/CFD Protein

Sequenz: Ile26-Ala253

Produktmerkmale: Recombinant Human Complement Factor D/CFD Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile26-Ala253.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human Complement Factor D, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-Complement Factor D Antibody, hFc Tag with the EC50 of 42.5ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Adipsin (CFD) (Complement Factor D (CFD))

Andere Bezeichnung: Complement Factor D (CFD Produkte)

Synonyme: ADIPSIN Protein, ADN Protein, DF Protein, PFD Protein, Adn Protein, Df Protein, EVE Protein, CFD Protein, adipsin Protein, pfd Protein, cfdl Protein, wu:fb61f12 Protein, zgc:109940 Protein, 10.5 Protein, 10.9 Protein, 14.10 Protein, 20.35 Protein, CG2328 Protein, Dmel\\CG2328 Protein, E(eve) Protein, Eve Protein, F Protein, V Protein, VI Protein, eve2 Protein, even Protein, l(2)46CFg Protein, l(2)46CFh Protein, l(2)46CFj Protein, l(2)46CFp Protein, l(2)46Ce Protein, l(2)46Cg Protein, complement factor D Protein, complement factor D (adipsin) Protein, complement factor D (adipsin) L homeolog Protein, even skipped Protein, CFD Protein, Cfd Protein, cfd.L Protein, cfd Protein, eve Protein

Hintergrund: Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

Molekulargewicht: 51.2 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.

Pathways: Komplementsystem