P-Cadherin Protein (CDH3) (AA 100-647) (His tag)

Produktnummer ABIN7274315

Produktdetails

Target: P-Cadherin (CDH3)

Protein-Typ: Recombinant

Proteineigenschaft: AA 100-647

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses P-Cadherin Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse CDH3/Cadherin 3 Protein

Sequenz: Glu100-Gly647

Produktmerkmale: Recombinant Mouse CDH3/Cadherin 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu100-Gly647.

Reinheit: > 90 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: P-Cadherin (CDH3)

Andere Bezeichnung: CDH3 (CDH3 Produkte)

Synonyme: CDH3 Protein, Cadherin-3 Protein, AI385538 Protein, Cadp Protein, Cdhp Protein, P-cadherin Protein, Pcad Protein, CDHP Protein, HJMD Protein, PCAD Protein, E-Cad Protein, E-cadherin Protein, EP-cadherin Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, cdh1 Protein, cdh1-b Protein, cdh3 Protein, cdhc-A Protein, cdhp Protein, hjmd Protein, l-cam Protein, lcam Protein, pcad Protein, uvo Protein, uvomorulin Protein, xb-cad Protein, xcdh1 Protein, CDH15 Protein, K-CAM Protein, cadherin 3 Protein, cadherin 3 L homeolog Protein, Cadherin-3 Protein, CDH3 Protein, Cdh3 Protein, cdh3.L Protein, cdh-3 Protein

Hintergrund: Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration.

Molekulargewicht: 64.68 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

UniProt: P10287