CD70 Protein (AA 39-193) (Fc Tag)
-
- Target Alle CD70 Proteine anzeigen
- CD70 (CD70 Molecule (CD70))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 39-193
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD70 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human CD27 Ligand/CD70 Protein
- Sequenz
- Gln39-Pro193
- Produktmerkmale
- Recombinant Human CD27 Ligand/CD70 Protein is expressed from HEK293 with hFc at the N-Terminus.It contains Gln39-Pro193.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CD27, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD27 Ligand, hFc Tag with the EC50 of 37.9ng/ml determined by ELISA. See testing image for detail.
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- CD70 (CD70 Molecule (CD70))
- Andere Bezeichnung
- CD27 Ligand (CD70 Produkte)
- Synonyme
- CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
- Hintergrund
- CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
- Molekulargewicht
- 42.7 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.
- Pathways
- Cancer Immune Checkpoints
-