TNFRSF8 Protein (AA 19-379) (Fc Tag)

Produktnummer ABIN7274148

Produktdetails

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-379

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNFRSF8 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human CD30/TNFRSF8 Protein

Sequenz: Phe19-Lys379

Produktmerkmale: Recombinant Human CD30/TNFRSF8 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Lys379.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CD30, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human CD30 Ligand, mFc Tag with the EC50 of 0.12μg/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Andere Bezeichnung: CD30 (TNFRSF8 Produkte)

Synonyme: CD30 Protein, D1S166E Protein, Ki-1 Protein, Cd30 Protein, Ki Protein, TNFRSF8 Protein, TNF receptor superfamily member 8 Protein, tumor necrosis factor receptor superfamily, member 8 Protein, TNFRSF8 Protein, Tnfrsf8 Protein

Hintergrund: The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).

Molekulargewicht: 65.2 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.