TNFRSF8 Protein (His tag)

Produktnummer ABIN6961166

Produktdetails

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNFRSF8 Protein ist gelabelt mit His tag.

Applikation: ELISA

Verwendungszweck: Recombinant human CD30 protein with C-terminal 6xHis tag

Spezifität: CD30 (Phe19-Lys379) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: affinity purification

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Konservierungsmittel: Without preservative

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Andere Bezeichnung: CD30 (TNFRSF8 Produkte)

Synonyme: CD30 Protein, D1S166E Protein, Ki-1 Protein, Cd30 Protein, Ki Protein, TNFRSF8 Protein, TNF receptor superfamily member 8 Protein, tumor necrosis factor receptor superfamily, member 8 Protein, TNFRSF8 Protein, Tnfrsf8 Protein

Hintergrund: Synonymes: TNFRSF8,CD30,D1S166E,Ki-1
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Molekulargewicht: predicted molecular mass of 39.3 kDa after removal of the signal peptide. The apparent molecular mass of CD30-His is 55-70 kDa due to glycosylation.

Gen-ID: 943

UniProt: P28908