CD21 Protein (AA 12-963) (His tag)

Produktnummer ABIN7276195

Produktdetails

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 12-963

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD21 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse CD21 Protein

Sequenz: Ile12-Trp963

Produktmerkmale: Recombinant Mouse CD21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile12-Trp963.

Reinheit: > 90 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Andere Bezeichnung: CD21 (CR2 Produkte)

Synonyme: C3DR Protein, CD21 Protein, CR Protein, CVID7 Protein, SLEB9 Protein, Cd21 Protein, cd21 Protein, CR1 Protein, CR1-L Protein, CR2 Protein, complement C3d receptor 2 Protein, complement C3b/C4b receptor 1 (Knops blood group) Protein, CR2 Protein, Cr2 Protein, CR1 Protein

Hintergrund: A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes.

Molekulargewicht: 106.03 kDa. Due to glycosylation, the protein migrates to 130-160 kDa based on Tris-Bis PAGE result.

UniProt: P19070

Pathways: Komplementsystem