APOA5 Protein (AA 21-368) (His tag)

Produktnummer ABIN7273849

Produktdetails

Target: APOA5 (Apolipoprotein A-V (APOA5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-368

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses APOA5 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse APOA5 Protein

Sequenz: Arg21-Gly368

Produktmerkmale: Recombinant Mouse APOA5 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Arg21-Gly368.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol, 2 mM DTT ( pH 8.5).

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: APOA5 (Apolipoprotein A-V (APOA5))

Andere Bezeichnung: APOA5 (APOA5 Produkte)

Synonyme: APOAV Protein, RAP3 Protein, 1300007O05Rik Protein, Apoav Protein, apo-AV Protein, apoA-V Protein, APOA5 Protein, MGC140487 Protein, rap3 Protein, apoav Protein, apoa-v Protein, apolipoprotein A5 Protein, apolipoprotein A-V Protein, apolipoprotein A5 L homeolog Protein, APOA5 Protein, Apoa5 Protein, apoa5.L Protein, apoa5 Protein

Hintergrund: APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological roles of apoAV have been recently elucidated, such as control of chylomicron production in the intestine and TG accumulation in adipose tissue.The key role of APOA5 in TG metabolism has been largely shown through genetic studies in association with either severe or moderate hypertriglyceridemia.

Molekulargewicht: 40.5 kDa same as Tris-Bis PAGE result.

UniProt: Q8C7G5

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism