SARS-CoV Spike (SARS-CoV S)
(SARS-Coronavirus Spike Protein (SARS-CoV S))
Protein-Typ
Recombinant
Proteineigenschaft
R648A, Trimer
Spezies
SARS Coronavirus (SARS-CoV)
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses SARS-CoV Spike Protein ist gelabelt mit His tag.
Verwendungszweck
BtRf-BetaCoV/JL2012 Spike Trimer (R648A, KV949-950PP), His Tag
Sequenz
Tyr 16 - Pro 1176
Produktmerkmale
BtRf-BetaCoV/JL2012 Spike Trimer, His Tag (SPN-S52Hs) is expressed from human 293 cells (HEK293). It contains AA Tyr 16 - Pro 1176 (Accession # A0A0U1UYX4-1 (R648A, KV949-950PP).
SARS-CoV S
Spezies: SARS Coronavirus (SARS-CoV)
Wirt: Escherichia coli (E. coli)
Recombinant
>90 %
ELISA
Applikationshinweise
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 133.3 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
PBS
Lagerung
-20 °C
Informationen zur Lagerung
-20°C
Target
SARS-CoV Spike (SARS-CoV S)
(SARS-Coronavirus Spike Protein (SARS-CoV S))
Synonyms:Spike,S protein,Spike glycoprotein,S glycoprotein,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.