CD79b Protein (Biotin,His-Avi Tag)

Produktnummer ABIN7319845

Produktdetails

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CD79b Protein ist gelabelt mit Biotin,His-Avi Tag.

Verwendungszweck: Recombinant Human CD79B/B29 (C-6His-Avi) Biotinylated

Sequenz: Ala29-Asp159

Produktmerkmale: Biotinylated Recombinant Human CD79B is produced by our Mammalian expression system and the target gene encoding Ala29-Asp159 is expressed with a 6His, Avi tag at the C-terminus.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Kommentare:

30-40 kDa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Andere Bezeichnung: CD79B (CD79B Produkte)

Synonyme: B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein

Hintergrund:

Background: CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

Synonym: B-Cell Antigen Receptor Complex-Associated Protein Beta Chain, B-Cell-Specific Glycoprotein B29, Ig-Beta, Immunoglobulin-Associated B29 Protein, CD79b, CD79B, B29, IGB

Molekulargewicht: 18.1 kDa

UniProt: P40259

Pathways: BCR Signaling