VEGFB Protein (Fc Tag)
-
- Target Alle VEGFB Proteine anzeigen
- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses VEGFB Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Human VEGF-B/VEGFB Protein (Fc Tag)
- Sequenz
- Pro22-Ala207
- Produktmerkmale
- Recombinant Human VEGFB is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a Fc tag at the N-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product VEGFB Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
- Andere Bezeichnung
- VEGF-B/VEGFB (VEGFB Produkte)
- Synonyme
- VEGFL Protein, VRF Protein, VEGF-B Protein, Vrf Protein, vascular endothelial growth factor B Protein, VEGFB Protein, Vegfb Protein
- Hintergrund
-
Background: VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.
Synonym: Vascular endothelial growth factor B,VEGF-B,VEGF-related factor,VRF
- Molekulargewicht
- 45.7 kDa
- UniProt
- P49765
- Pathways
- RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
-