VEGFB Protein (Fc Tag)

Produktnummer ABIN7319412

Produktdetails

Target: VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses VEGFB Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human VEGF-B/VEGFB Protein (Fc Tag)

Sequenz: Pro22-Ala207

Produktmerkmale: Recombinant Human VEGFB is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a Fc tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

Andere Bezeichnung: VEGF-B/VEGFB (VEGFB Produkte)

Synonyme: VEGFL Protein, VRF Protein, VEGF-B Protein, Vrf Protein, vascular endothelial growth factor B Protein, VEGFB Protein, Vegfb Protein

Hintergrund:

Background: VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.

Synonym: Vascular endothelial growth factor B,VEGF-B,VEGF-related factor,VRF

Molekulargewicht: 45.7 kDa

UniProt: P49765

Pathways: RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals