VCP Protein (His tag)

Produktnummer ABIN7319166

Produktdetails

Target: VCP (Valosin Containing Protein (VCP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses VCP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human VCP Protein (His Tag)

Sequenz: Ala2-Asn589

Produktmerkmale: Recombinant Human Valosin-Containing Protein is produced by our E.coli expression system and the target gene encoding Ala2-Asn589 is expressed with a 6His tag at the C-terminus.

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM TrisHCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: VCP (Valosin Containing Protein (VCP))

Andere Bezeichnung: VCP (VCP Produkte)

Synonyme: ALS14 Protein, IBMPFD Protein, TERA Protein, p97 Protein, CDC48 Protein, wu:fd16d05 Protein, wu:fj63d11 Protein, p93 Protein, 3110001E05 Protein, p97/VCP Protein, 22.26 Protein, 7.12 Protein, Apple Protein, BcDNA.GM02885 Protein, BcDNA:GM02885 Protein, CG2331 Protein, DmTER94 Protein, Dmel\CG2331 Protein, I Protein, Ter94 Protein, Tera Protein, VCP Protein, VCP ATPase Protein, VCP/p97 Protein, Vcp Protein, anon-WO2004063362.65 Protein, anon-WO2004063362.67 Protein, cdc48 Protein, dTERA Protein, dVCP Protein, dmTERA Protein, dvcp Protein, l(2)03775 Protein, l(2)46CFf Protein, l(2)46CFs Protein, l(2)46Ch Protein, pTER94 Protein, ter94 Protein, vcp Protein, FANCG Protein, valosin containing protein Protein, valosin containing protein S homeolog Protein, valosin-containing protein Protein, CG2331 gene product from transcript CG2331-RA Protein, zgc:136908 Protein, transitional endoplasmic reticulum ATPase Protein, VCP Protein, vcp.S Protein, vcp Protein, Vcp Protein, Bm1_56585 Protein, LOC100136246 Protein, TER94 Protein, zgc:136908 Protein, LOC101109680 Protein

Hintergrund:

Background: Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP participates in the formation of the transitional endoplasmic reticulum (tER) and regulates E3 ubiquitin-protein ligase activity of RNF19A.

Synonym: Transitional Endoplasmic Reticulum ATPase, TER ATPase, 15S Mg(2+)-ATPase p97 Subunit, Valosin-Containing Protein, VCP

Molekulargewicht: 66.4 kDa

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway