UBE2C Protein (His tag)
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- Target Alle UBE2C Proteine anzeigen
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses UBE2C Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human UBE2C Protein (His Tag)
- Sequenz
- Met 1-Pro179
- Produktmerkmale
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 C is produced by our E.coli expression system and the target gene encoding Met1-Pro179 is expressed with a 6His tag at the N-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UBE2C Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Andere Bezeichnung
- UBE2C (UBE2C Produkte)
- Synonyme
- LOC458287 Protein, UBCH10 Protein, dJ447F3.2 Protein, 1110015A16Rik Protein, D2Ertd695e Protein, im:7137135 Protein, zgc:123190 Protein, ubiquitin conjugating enzyme E2 C Protein, ubiquitin-conjugating enzyme E2C Protein, ubiquitin conjugating enzyme E2 C L homeolog Protein, ubiquitin conjugating enzyme E2 C S homeolog Protein, UBE2C Protein, NAEGRDRAFT_82946 Protein, ube2c.L Protein, Ube2c Protein, ube2c.S Protein, ube2c Protein
- Hintergrund
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Background: Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).
Synonym: Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C, UBCH10
- Molekulargewicht
- 23.3 kDa
- UniProt
- O00762
- Pathways
- Ubiquitin Proteasome Pathway
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