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TXNRD1 Protein (AA 161-647) (His tag)

TXNRD1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7198225
  • Target Alle TXNRD1 Proteine anzeigen
    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 161-647
    Spezies
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 7
    • 6
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses TXNRD1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human TXNRD1/TRXR1 Protein (aa 161-647, His Tag)
    Sequenz
    Tyr 161-Cys 647
    Produktmerkmale
    A DNA sequence encoding the human TXNRD1 isoform 1 (Q16881-1) (Tyr 161-Cys 647) was expressed, with a polyhistide tag at the N-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product TXNRD1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
    Andere Bezeichnung
    TXNRD1/TRXR1 (TXNRD1 Produkte)
    Synonyme
    TrxR1 Protein, cb682 Protein, fb83a08 Protein, wu:fb83a08 Protein, GB14972 Protein, MGC85342 Protein, NADPH-dependent thioredoxin reductase C Protein, T32G6.20 Protein, T32G6_20 Protein, GRIM-12 Protein, TR Protein, TR1 Protein, TRXR1 Protein, TXNR Protein, Tr Protein, thioredoxin reductase 1 Protein, thioredoxin reductase 1 L homeolog Protein, NADPH-dependent thioredoxin reductase C Protein, ThioRedoXin Reductase Protein, TXNRD1 Protein, txnrd1 Protein, Trxr-1 Protein, txnrd1.L Protein, NTRC Protein, trxr-1 Protein, Txnrd1 Protein
    Hintergrund

    Background: Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.

    Synonym: GRIM-12,TR,TR1,TRXR1,TXNR

    Molekulargewicht
    55 kDa
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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