ST8SIA1 Protein (His tag)

Produktnummer ABIN7319204

Produktdetails

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses ST8SIA1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ST8SIA1 Protein (His Tag)

Sequenz: Tyr49-Ser356

Produktmerkmale: Recombinant Human alpha-N-Acetylneuraminide alpha-2,8-Sialyltransferase is produced by our Mammalian expression system and the target gene encoding Tyr49-Ser356 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Andere Bezeichnung: ST8SIA1 (ST8SIA1 Produkte)

Synonyme: SIAL-T2 Protein, Xlgd3 Protein, siat8 Protein, siat8a Protein, st8sial Protein, st8siaI Protein, ST8SIA1 Protein, St8sia1 Protein, GD3S Protein, SIAT8 Protein, SIAT8-A Protein, SIAT8A Protein, ST8SiaI Protein, 9330109E03Rik Protein, Sia-T Protein, Siat8 Protein, Siat8a Protein, ST8SIA-IV Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 L homeolog Protein, ST8SIA1 Protein, st8sia1.L Protein, st8sia1 Protein, St8sia1 Protein

Hintergrund:

Background: α-N-Acetylneuraminide α-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.

Synonym: Alpha-N-Acetylneuraminide Alpha-2,8-Sialyltransferase, Alpha-2,8-Sialyltransferase 8A, Ganglioside GD3 Synthase, Ganglioside GT3 Synthase, Sialyltransferase 8A, SIAT8-A, Sialytransferase St8Sia I, ST8SiaI, ST8SIA1, SIAT8, SIAT8A

Molekulargewicht: 36.2 kDa

UniProt: Q92185