ST8SIA1 Protein (AA 49-356) (His tag)

Produktnummer ABIN4370452

Produktdetails

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 49-356

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses ST8SIA1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human α-N-Acetylneuraminide α-2,8-Sialyltransferase/ST8SIA1 (C-6His)

Sequenz: YRLPNEKEIV QGVLQQGTAW RRNQTAARAF RKQMEDCCDP AHLFAMTKMN SPMGKSMWYD GEFLYSFTID NSTYSLFPQA TPFQLPLKKC AVVGNGGILK KSGCGRQIDE ANFVMRCNLP PLSSEYTKDV GSKSQLVTAN PSIIRQRFQN LLWSRKTFVD NMKIYNHSYI YMPAFSMKTG TEPSLRVYYT LSDVGANQTV LFANPNFLRS IGKFWKSRGI HAKRLSTGLF LVSAALGLCE EVAIYGFWPF SVNMHEQPIS HHYYDNVLPF SGFHAMPEEF LQLWYLHKIG ALRMQLDPCE DTSLQPTSVD HHHHHH

Produktmerkmale: Recombinant Human alpha-N-Acetylneuraminide alpha-2,8-Sialyltransferase/ST8SIA1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Tyr49-Ser356) of Human ST8SIA1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Andere Bezeichnung: alpha-2-8-Sialyltransferase-8A (ST8SIA1 Produkte)

Synonyme: SIAL-T2 Protein, Xlgd3 Protein, siat8 Protein, siat8a Protein, st8sial Protein, st8siaI Protein, ST8SIA1 Protein, St8sia1 Protein, GD3S Protein, SIAT8 Protein, SIAT8-A Protein, SIAT8A Protein, ST8SiaI Protein, 9330109E03Rik Protein, Sia-T Protein, Siat8 Protein, Siat8a Protein, ST8SIA-IV Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 L homeolog Protein, ST8SIA1 Protein, st8sia1.L Protein, st8sia1 Protein, St8sia1 Protein

Sub Type: Fusionprotein

Hintergrund: Alpha-N-Acetylneuraminide alpha-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.
Alternative Names: Alpha-N-Acetylneuraminide Alpha-2,8-Sialyltransferase, Alpha-2,8-Sialyltransferase 8A, Ganglioside GD3 Synthase, Ganglioside GT3 Synthase, Sialyltransferase 8A, SIAT8-A, Sialytransferase St8Sia I, ST8SiaI, ST8SIA1, SIAT8, SIAT8A

Molekulargewicht: 36.2 kDa

UniProt: Q92185