SHMT1 Protein (His tag)

Produktnummer ABIN7319012

Produktdetails

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SHMT1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SHMT1 Protein (His Tag)

Sequenz: Met3-Phe483

Produktmerkmale: Recombinant Human Serine Hydroxymethyltransferase Cytosolic is produced by our Mammalian expression system and the target gene encoding Met3-Phe483 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Andere Bezeichnung: SHMT1 (SHMT1 Produkte)

Synonyme: Shmt Protein, mShmt Protein, LRRGT00032 Protein, shmt1 Protein, MGC53442 Protein, zgc:66171 Protein, zgc:77524 Protein, SHMT1 Protein, Shmt1 Protein, CSHMT Protein, SHMT Protein, AI324848 Protein, AI385541 Protein, C81125 Protein, mshmt Protein, mshmt1 Protein, mshmt2 Protein, MEL-32 Protein, SHMT2 Protein, F20D10.50 Protein, F20D10_50 Protein, SERINE HYDROXYMETHYLTRANSFERASE 1 Protein, SERINE TRANSHYDROXYMETHYLASE Protein, SERINE TRANSHYDROXYMETHYLTRANSFERASE Protein, STM Protein, serine transhydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 (soluble) L homeolog Protein, serine hydroxymethyltransferase 1 (soluble) Protein, microRNA 6778 Protein, serine transhydroxymethyltransferase 1 Protein, Shmt1 Protein, shmt1.L Protein, shmt1 Protein, MIR6778 Protein, SHMT1 Protein, SHM1 Protein

Hintergrund:

Background: Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.

Synonym: Serine Hydroxymethyltransferase Cytosolic, SHMT, Glycine Hydroxymethyltransferase, Serine Methylase, SHMT1

Molekulargewicht: 53.9 kDa

UniProt: P34896