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SHMT1 Produkte

(serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Kategorien

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Ausgewählte SHMT1 Kategorien

SHMT1 Antikörper

High quality antibodies with extensive validation data.

SHMT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SHMT1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SHMT1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (1)
  • (7)
Kat. Nr. ABIN562870
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7256154
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN6147744
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SHMT1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959375
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1156948
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1156949
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SHMT1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319951
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319953
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125034
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SHMT1 Produkten

Sage, Ron-Harel, Juneja, Sen, Maleri, Sungnak, Kuchroo, Haining, Chevrier, Haigis, Sharpe: "Suppression by TFR cells leads to durable and selective inhibition of B cell effector function." in: Nature immunology, Vol. 17, Issue 12, pp. 1436-1446, (2016) (PubMed).

Sun, Song, Wan, Wu, Li, Wang, Wang, Liu, Zhong, He, Shen, Pan, Li, Wang, Gao, Tang, Zhang: "cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions." in: Cell research, Vol. 25, Issue 4, pp. 429-44, (2015) (PubMed).

Genovese, Gualandi, Taddia, Marverti, Pirondi, Marraccini, Perco, Pelà, Guerrini, Amoroso, Esposito, Martello, Ponterini, DArca, Costi: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).

Wei, Sun, Sandoval, Cross, Gordon, Kang, Roje: "Folate polyglutamylation eliminates dependence of activity on enzyme concentration in mitochondrial serine hydroxymethyltransferases from Arabidopsis thaliana." in: Archives of biochemistry and biophysics, Vol. 536, Issue 1, pp. 87-96, (2013) (PubMed).

Nilsson, Forshell, Rimpi, Kreutzer, Pretsch, Bornkamm, Nilsson: "Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis." in: PLoS genetics, Vol. 8, Issue 3, pp. e1002573, (2012) (PubMed).

Synonyme und alternative Namen zu SHMT1

serine hydroxymethyltransferase 1 (Shmt1), serine hydroxymethyltransferase 1 (soluble) L homeolog (shmt1.L), serine hydroxymethyltransferase 1 (soluble) (shmt1), microRNA 6778 (MIR6778), serine hydroxymethyltransferase 1 (SHMT1), serine hydroxymethyltransferase 1 (soluble) (Shmt1), serine transhydroxymethyltransferase 1 (SHM1), AI324848, AI385541, C81125, CSHMT, F20D10.50, F20D10_50, LRRGT00032, MEL-32, MGC53442, mShmt, mshmt, mshmt1, mshmt2, SERINE HYDROXYMETHYLTRANSFERASE 1, SERINE TRANSHYDROXYMETHYLASE, SERINE TRANSHYDROXYMETHYLTRANSFERASE, serine transhydroxymethyltransferase 1, Shmt, SHMT, shmt1, SHMT1, Shmt1, SHMT2, STM, zgc:66171, zgc:77524

Bezeichner auf Proteinebene für SHMT1

  • serine hydroxymethyltransferase, cytosolic
  • serine hydroxymethyltransferase 1 (soluble)
  • zSHMT-1
  • SHMT
  • glycine hydroxymethyltransferase
  • serine methylase
  • cytoplasmic serine hydroxymethyltransferase
  • cytosolic serine hydroxymethyltransferase
  • serine hydroxymethyl transferase
  • serine hydroxymethyltransferase 2 (mitochondrial)
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