S100A7A Protein (His tag,MBP tag)

Produktnummer ABIN7320360

Produktdetails

Target: S100A7A (S100 Calcium Binding Protein A7A (S100A7A))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses S100A7A Protein ist gelabelt mit His tag,MBP tag.

Verwendungszweck: Recombinant Mouse S100A15/S100A7A Protein (His & MBP Tag)

Sequenz: Met 1-Tyr 108

Produktmerkmale: A DNA sequence encoding the mouse S100A7A (Q6S5I3) (Met 1-Tyr 108) was fused with the N-terminal polyhistidine-tagged MBP tag at the N-terminus.

Reinheit: > 90 % as determined by SDS-PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.5

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: S100A7A (S100 Calcium Binding Protein A7A (S100A7A))

Andere Bezeichnung: S100A15/S100A7A (S100A7A Produkte)

Synonyme: NICE-2 Protein, S100A15 Protein, S100A7L1 Protein, S100A7f Protein, AY465109 Protein, Gm1020 Protein, S100a15 Protein, S100a15a Protein, S100a17l1 Protein, S100 calcium binding protein A7A Protein, Protein S100-A15A Protein, S100A7A Protein, S100a7a Protein, S100A15A Protein

Hintergrund:

Background: Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype. The association of the 11.2 kDa S100A7A / S100A15 with psoriasis suggests that it contributes to the pathogenesis of the disease and could provide a molecular target for therapy. 

Synonym: AY465109;Gm1020;S100a15;S100a15a;S100a17l1;S100A7f;S100A7L1

Molekulargewicht: 56.5 kDa

UniProt: Q6S5I3

Pathways: Activation of Innate immune Response, S100 Proteine