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PKLR Protein (His tag)

PKLR Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318973
  • Target Alle PKLR Proteine anzeigen
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 4
    • 3
    • 2
    • 1
    Human
    Quelle
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses PKLR Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human PKLR Protein (His Tag)
    Sequenz
    Met 1-Ser574
    Produktmerkmale
    Recombinant Human Pyruvate Kinase, Liver And RBC is produced by our Mammalian expression system and the target gene encoding Met1-Ser574 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PKLR Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 1 mM DTT 0.2M NaCl, 10 % glycerol, pH 8.0.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    Andere Bezeichnung
    PKLR (PKLR Produkte)
    Synonyme
    PK1 Protein, PKL Protein, PKR Protein, PKRL Protein, RPK Protein, Pklg Protein, wu:fd15e01 Protein, wu:fi37e08 Protein, pk1 Protein, PKLR Protein, Pk-1 Protein, Pk1 Protein, R-PK Protein, pklr Protein, pyruvate kinase L/R Protein, pyruvate kinase, liver and RBC Protein, pyruvate kinase, liver and RBC L homeolog Protein, pyruvate kinase liver and red blood cell Protein, pyruvate kinase PKLR-like Protein, PKLR Protein, Pklr Protein, pklr Protein, pklr.L Protein, LOC100621940 Protein
    Hintergrund

    Background: Pyruvate Kinase Isozymes R/L (PKLR) belongs to the pyruvate kinase family, There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver, R is found in red cells, M1 is the main form in muscle, heart and brain, M2 is found in early fetal tissues. PKLR exists as a homotetramer and catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in PKLR are also the cause of pyruvate kinase deficiency of red cells, which is a frequent cause of hereditary non-spherocytic hemolytic anemia.

    Synonym: Pyruvate Kinase Isozymes R/L, Pyruvate Kinase 1, R-Type/L-Type Pyruvate Kinase, Red Cell/Liver Pyruvate Kinase, PKLR, PK1, PKL

    Molekulargewicht
    62.9 kDa
    UniProt
    P30613
    Pathways
    Ribonucleoside Biosynthetic Process
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