PLTP Protein (His tag)

Produktnummer ABIN7317633

Produktdetails

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PLTP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PLTP Protein (His Tag)

Sequenz: Met 1-Val 493

Produktmerkmale: A DNA sequence encoding the human PLTP isoform 1 (P55058-1) (Met 1-Val 493) was expressed, fused with a polyhistidine tag at the C-terminus.

Reinheit: > 80 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Andere Bezeichnung: PLTP (PLTP Produkte)

Synonyme: zgc:100903 Protein, MGC84445 Protein, PLTP Protein, hdlcq9 Protein, DKFZp469A1437 Protein, BPIFE Protein, HDLCQ9 Protein, Bpife Protein, OD107 Protein, phospholipid transfer protein Protein, phospholipid transfer protein S homeolog Protein, PLTP Protein, pltp Protein, pltp.S Protein, LOC542343 Protein, Pltp Protein

Hintergrund:

Background: Phospholipid transfer protein, also known as Lipid transfer protein II and PLTP, is a secreted protein which belongs to the BPI/LBP/Plunc superfamily and BPI / LBP family. PLTP is nearly ubiquitously expressed in cells and tissues. PLTP converts HDL into larger and smaller particles. It may play a key role in extracellular phospholipid transport and modulation of hdl particles. High-density lipoproteins (HDL) play a major protective role against the development of coronary artery disease. PLTP is a main factor regulating the size and composition of HDL in the circulation and plays an important role in controlling plasma HDL levels. This is achieved via both the phospholipid transfer activity of PLTP and its capability to cause HDL conversion. PLTP is one of the key lipid transfer proteins in plasma and cerebrospinal fluid. It is involved in novel intracellular functions. PLTP is an important modulator of lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL. PLTP also plays an important role in inflammation and oxidative stress. Accordingly, PLTP has also been implicated in the development of atherosclerosis.

Synonym: BPIFE;HDLCQ9

Molekulargewicht: 54.5 kDa

Pathways: Lipid Metabolism