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PI3 Protein (His tag)

PI3 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318425
  • Target Alle PI3 Proteine anzeigen
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 1
    Human
    Quelle
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses PI3 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human PI3/Elafin Protein (His Tag)
    Sequenz
    Ala23-Gln117
    Produktmerkmale
    Recombinant Human Elafin is produced by our Mammalian expression system and the target gene encoding Ala23-Gln117 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PI3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Andere Bezeichnung
    PI3/Elafin (PI3 Produkte)
    Synonyme
    ESI Protein, SKALP Protein, WAP3 Protein, WFDC14 Protein, cementoin Protein, trappin-2 Protein, TRAPPIN-2 Protein, elafin Protein, peptidase inhibitor 3 Protein, peptidase inhibitor 3, skin-derived (SKALP) Protein, PI3 Protein
    Hintergrund

    Background: Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.

    Synonym: Elafin, Elastase-Specific Inhibitor, ESI, Peptidase Inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-Derived Antileukoproteinase, SKALP, WAP Four-Disulfide Core Domain Protein 14, PI3, WAP3, WFDC14

    Molekulargewicht
    11.0 kDa
    UniProt
    P19957
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