Macrophage Scavenger Receptor 1 Protein (MSR1) (His tag)

Produktnummer ABIN7321106

Produktdetails

Target: Macrophage Scavenger Receptor 1 (MSR1)

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Macrophage Scavenger Receptor 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Rat MSR1/SCARA1/CD204 Protein (His Tag)

Sequenz: Trp79-Ser454

Produktmerkmale: A DNA sequence encoding the rat MSR1 (NP_001178868.1) (Trp79-Ser454) was expressed with a polyhistidine tag at the N-terminus.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Macrophage Scavenger Receptor 1 (MSR1)

Andere Bezeichnung: MSR1/SCARA1/CD204 (MSR1 Produkte)

Synonyme: CD204 Protein, SCARA1 Protein, SR-A Protein, SRA Protein, phSR1 Protein, phSR2 Protein, MRS-A Protein, MSR Protein, MSR-A Protein, SR-AI Protein, SR-AII Protein, Scara1 Protein, Scvr Protein, MSR1 Protein, RGD1564316 Protein, macrophage scavenger receptor 1 Protein, scavenger receptor class A member 5 Protein, MSR1 Protein, Msr1 Protein, SCARA5 Protein

Hintergrund:

Background: Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1 and SCARA1, is a single-pass type I I membrane protein which contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

Synonym: MSR1

Molekulargewicht: 43.1 kDa

NCBI Accession: NP_001178868