Lamin B1 Protein (LMNB1) (His tag)

Produktnummer ABIN7321291

Produktdetails

Target: Lamin B1 (LMNB1)

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Lamin B1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Rat Lamin B1 Protein (His Tag)

Sequenz: Arg387-Met587

Produktmerkmale: A DNA sequence encoding the Rat Lamin B1 (P70615-1) (Arg387-Met587) was expressed with a polyhistidine tag at the N-terminus.

Reinheit: >90 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: Lamin B1 (LMNB1 Produkte)

Synonyme: MGC52550 Protein, Lamin-L(I) Protein, lamin-b Protein, lmn Protein, lmn2 Protein, lmnb Protein, LMNB1 Protein, ADLD Protein, LMN Protein, LMN2 Protein, LMNB Protein, fc06g01 Protein, wu:fc06g01 Protein, lamin B1 L homeolog Protein, lamin B1 Protein, lmnb1.L Protein, lmnb1 Protein, LMNB1 Protein, Lmnb1 Protein

Hintergrund:

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Synonym: ADLD,lamin B1,Lamin-B1,LMN,LMN2,LMNB,Lmnb1,LMNB1,MGC111419,OTTHUMP00000159218

Molekulargewicht: 22.1 kDa

Pathways: Apoptose, Caspase Kaskade in der Apoptose