Kallikrein 4 Protein (His tag)

Produktnummer ABIN7318698

Produktdetails

Target: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Kallikrein 4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Kallikrein 4/KLK4 Protein (His Tag)

Sequenz: Ser27-Ser254

Produktmerkmale: Recombinant Human Kallikrein 4 is produced by our Mammalian expression system and the target gene encoding Ser27-Ser254 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Andere Bezeichnung: Kallikrein 4/KLK4 (KLK4 Produkte)

Synonyme: ESMP1 Protein, KLK-L1 Protein, PSTS Protein, Prss17 Protein, AI2A1 Protein, ARM1 Protein, EMSP Protein, EMSP1 Protein, PRSS17 Protein, kallikrein Protein, Emsp1 Protein, kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) Protein, kallikrein related peptidase 4 Protein, kallikrein-related peptidase 4 Protein, Klk4 Protein, KLK4 Protein

Hintergrund:

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Synonym: Kallikrein-4, Enamel Matrix Serine Proteinase 1, Kallikrein-Like Protein 1, KLK-L1, Prostase, Serine Protease 17, KLK4, EMSP1, PRSS17, PSTS,AI2A1,ARM1,EMSP,kallikrein,KLK-L1

Molekulargewicht: 25.4 kDa

UniProt: Q9Y5K2

Pathways: Komplementsystem