Kallikrein 1 Protein (KLK1) (His tag)

Produktnummer ABIN7196654

Produktdetails

Target: Kallikrein 1 (KLK1)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Kallikrein 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Kallikrein 1/KLK1 Protein (His Tag)(Active)

Sequenz: Met 1-Ser 262

Produktmerkmale: A DNA sequence encoding the human KLK1 (NP_002248.1) precursor (Met 1-Ser 262) was expressed with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is >1,500 pmoles/min/μg.(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Kallikrein 1 (KLK1)

Andere Bezeichnung: Kallikrein 1/KLK1 (KLK1 Produkte)

Synonyme: KLKR Protein, Klk6 Protein, hK1 Protein, klkr Protein, kallikrein Protein, 0610007D04Rik Protein, Kal Protein, Klk1b6 Protein, mGk-6 Protein, kallikrein 1 Protein, kallikrein 1 L homeolog Protein, KLK1 Protein, klk1.L Protein, LOC100101620 Protein, Klk1 Protein

Hintergrund:

Background: Human tissue kallikrein (KLK1) is a serine protease, component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its antiinflammatory, antiapoptotic, antifibrotic and antioxidative actions.Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension.

Synonym: Kallikrein-1, Kidney/Pancreas/Salivary Gland Kallikrein, Tissue Kallikrein, KLK1

Molekulargewicht: 28 kDa

NCBI Accession: NP_002248

Pathways: Komplementsystem