IL22RA2 Protein (His tag,Fc Tag)

Produktnummer ABIN7317690

Produktdetails

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL22RA2 Protein ist gelabelt mit His tag,Fc Tag.

Verwendungszweck: Recombinant Human IL-22BP/IL22RA2 Protein (His & Fc Tag)

Sequenz: Met 1-Pro 231

Produktmerkmale: A DNA sequence encoding the human IL22RA2 isoform 2 (NP_851826.1) (Met 1-Pro 231) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Andere Bezeichnung: IL-22BP/IL22RA2 (IL22RA2 Produkte)

Synonyme: CRF2-10 Protein, CRF2-S1 Protein, CRF2X Protein, IL-22BP Protein, IL-22R-alpha-2 Protein, IL-22RA2 Protein, ZCYTOR16 Protein, CRF2-s1 Protein, Il-22bp Protein, Crf2-s1 Protein, interleukin 22 receptor subunit alpha 2 Protein, interleukin 22 receptor, alpha 2 Protein, IL22RA2 Protein, Il22ra2 Protein

Hintergrund:

Background: Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type I I cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in placenta, spleen, breast, skin and lung. It is also detected in intestinal tract, testis, brain, heart and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important roles in immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptor have been discovered, a membrane-bound receptor and a soluble receptor.

Synonym: CRF2-10,CRF2-S1,CRF2X,IL-22BP,IL-22R-alpha-2,IL-22RA2,ZCYTOR16

Molekulargewicht: 52.8 kDa

NCBI Accession: NP_851826